Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans

June 3, 2008 PET, hallucinogen, in vivo 2 Comments

Jacob Hooker and colleagues have a new paper in which they labeled the active ingredient of Salvia divinorum with 11C and used PET to measure the drug’s pharmacokinetics in baboons after injection. Salvinorin A is a strange drug with a kappa-opioid receptor mechanism and is anecdotally said to produce more profound alterations in sense of self than most other hallucinogens.
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